All the characters except Professor Farnsworth and Zapp Brannigan die but they are all resuscitated.
Scruffy The Janitor, Kif Kroker and LaBarbara Conrad shoot from the rebirth machine and land on Dr. Zoidberg - Fry refers to them as "and the rest", a reference to the opening theme of Gilligan's Island.
The Leela-bot calls Nibbler by a pet name, "Pooperdoodle".
When Bender is thrown out of Studio 1²2¹3³ and lands on his back, he is able to roll himself over from having watched a turtle get up in Crimes of the Hot.
When the Professor is telling what REALLY happened, he says "It's like a comedy central channel, and we're on it now!" and that's a reference to Futurama changing channels from Fox to Comedy Central.
When the Professor is telling what REALLY happened, Bender says "Yeah. We're back." which is a reference to that Futurama is back after 7 years.
Bender singing "coma coma coma coma coma chameleon" is a reference to the song Karma Chameleon by Culture Club.
When this episode aired in Australia, Bender's voiceover lines at the beginning of the episode are different.
Bender's suit and dancing are a reference to Saturday Night Fever.
This is the first time a Planet express member has committed a very serious and unforgivable crime, which is murder. Farnsworth committed murder on several adults to harvest their stem cells in order to resuscitate his crew.
The Birth machine is one of only a few machines that Farnsworth invented that have actually worked.